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Dapsone

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Disclaimer: This page provides general information about Aczone for people in New Zealand. It is not a substitute for professional medical advice. Always check the official leaflet or consult your doctor or pharmacist for personalised guidance.

What is Aczone?

Aczone is a topical medicine used on the skin. It contains the active ingredient dapsone as a gel preparation that is applied to areas affected by acne. The gel is intended for external use only and should not be swallowed or used on mucous membranes.

Aczone is designed to act locally on the skin where it is applied. It is intended to be used as part of a broader acne treatment plan that may include skincare routines and other therapies prescribed by a clinician. Depending on local rules, access to Aczone may require a prescription from a clinician or pharmacist.

When you start Aczone, it is important to follow the directions given by your clinician and to use only on skin that has not been damaged or irritated. If you have a known allergy to dapsone or related medicines, inform your clinician before using the product.

Store Aczone in its original packaging, at room temperature, away from heat and moisture. Keep it out of the reach of children. If the appearance, smell, or texture changes, talk to a pharmacist about whether to continue using it.

What is it used for?

Aczone is used to treat acne vulgaris, particularly inflammatory lesions such as red bumps and pustules on the face. It may also be used on other areas of the body as advised by a clinician. It is not a cure for acne, but it can help control symptoms when used as part of a broader management plan.

It provides a local action on the skin, rather than affecting the whole body. This makes it different from some oral medications that treat acne systemically. Your clinician will determine whether Aczone is appropriate for your specific acne pattern.

Response to treatment can vary between individuals. Some people notice improvement after several weeks of regular use, while others may require a longer period to see a noticeable difference. Continued use as directed is important even if early results are slow.

Alongside Aczone, your clinician may recommend complementary skincare habits or other acne therapies. If your acne is severe or not improving, discuss this with your clinician to review the treatment plan.

How it works

Aczone contains dapsone, a medicine with anti-inflammatory properties and activity against certain bacteria that can contribute to acne. By reducing inflammation and targeting acne-causing organisms on the skin, it helps lessen redness and swelling in affected areas.

The gel is applied to the surface of the skin, so the action is primarily local. This means most of the effect is on the area where it is applied, with less systemic absorption compared with some oral medicines. However, some people may experience skin irritation or other local effects.

The exact way Aczone improves acne is not fully understood, but its anti-inflammatory effects are a key part of the mechanism. It may help prevent the cycle of irritation that leads to pustules and redness in acne-prone skin.

Because Aczone acts mainly on the skin, most people experience side effects related to the application area rather than systemic effects. If you notice any unusual or persistent symptoms, contact your clinician for guidance.

How to use Aczone

Read the patient information leaflet and follow your clinician’s instructions before first use. If you have any questions, ask your pharmacist or clinician for clarification. Use only as directed for your specific acne pattern and skin type.

Apply a thin layer to the affected areas once daily, or as directed by your clinician. Do not apply to large areas of skin unless advised. A thin layer helps ensure the gel dries properly and minimizes potential irritation.

Wash your hands before applying the gel and after applying it. Avoid contact with eyes, mouth, and inside the nose. If contact occurs, rinse thoroughly with water.

If you use other skin products, apply them according to your clinician’s advice. You may need to wait for the Aczone gel to dry before applying other products, or you may be advised to use products at different times of day.

If you accidentally apply more gel than directed, wipe away the excess with a clean tissue and rinse the area with water. If you miss a dose, apply as soon as you remember unless it is almost time for the next dose; do not double dose to make up for the skipped application.

Who should avoid Aczone?

Do not use Aczone if you have a known allergy to dapsone or any of the components in the gel. An allergic reaction can be serious and requires medical attention.

Tell your clinician about any health conditions you have, especially those affecting the blood or liver, or a history of methaemoglobinaemia or glucose-6-phosphate dehydrogenase (G6PD) deficiency. These conditions may influence how the medicine should be used in your case.

Aczone is intended for use on the skin. Do not apply to broken, irritated, or sunburned skin unless advised by a clinician. Avoid applying near mucous membranes or into the eyes, unless directed otherwise.

If you are pregnant, planning a pregnancy, or breastfeeding, discuss use with your clinician. The safety of Aczone in pregnancy and breastfeeding has not been established in all situations, so medical advice is important.

Warnings

Skin irritation is a common experience when starting Aczone. If irritation persists or becomes severe, contact your clinician. They may adjust the dose or suggest a different treatment.

Sun exposure can increase skin sensitivity in treated areas. Use broad‑spectrum sunscreen, wear protective clothing, and limit direct sun exposure on treated skin while using Aczone.

Avoid applying Aczone on large areas of skin or on damaged skin unless explicitly advised by your clinician. If you notice any unusual skin reactions, consult your clinician promptly.

Tell your clinician about all medicines you use, including other topical products, vitamins, and herbal supplements. Some products may interact with dapsone or increase irritation. Do not start or stop other acne treatments without professional guidance.

If you experience signs of a severe allergic reaction, such as swelling of the face or tongue, difficulty breathing, or fainting, seek urgent medical help immediately. These reactions are rare but require prompt attention.

Side effects

Most people tolerate Aczone well. The most common side effects are local to the skin where the gel is applied. These can include redness, dryness, burning, itching, or a stinging sensation at the treated area.

Some people may notice temporary changes in skin color in treated areas, such as lightening or darkening of the skin. These changes are usually reversible after stopping treatment but should be discussed with your clinician if there is concern.

Less commonly, people may develop more pronounced irritation, peeling or a rash on the treated skin. If irritation is persistent or worsening, stop use and contact your clinician for advice.

In very rare cases, systemic effects may occur, although these are not common with topical dapsone. If you experience dizziness, fever, or unusually tiredness, seek medical advice promptly.

Seek urgent medical help if you notice signs of an allergic reaction, such as swelling of the face, lips, tongue, or throat, or difficulty breathing after applying the gel. This requires immediate evaluation by a healthcare professional.

Interactions

Tell your clinician about all medicines you are using, including other topical products, vitamins, and herbal supplements. Some substances may interact with Aczone or increase the chance of irritation.

Avoid combining Aczone with other acne medicines unless advised by your clinician. They can help determine if a change to your regimen is needed to reduce irritation or overlap of effects.

If you are taking systemic medicines, especially those that affect the blood or immune system, discuss potential interactions with your clinician. They can assess whether any adjustments are needed for safety and effectiveness.

There is no well-known interaction between Aczone and alcohol that would require avoiding alcohol, but always follow your clinician’s advice and report any unusual symptoms after starting Aczone.

If you notice a new or worsening reaction after applying Aczone alongside another product, contact your clinician for guidance on how to proceed. Do not change your treatment plan without professional input.

Pregnancy and breastfeeding

The safety of Aczone during pregnancy has not been fully established in all circumstances. If you are pregnant or plan to become pregnant, discuss the benefits and risks with your clinician before starting or continuing treatment.

If you are planning pregnancy or become pregnant while using Aczone, your clinician can help determine whether to continue or adjust treatment. Breastfeeding safety has not been fully established in all situations, so discuss it with your clinician if you are breastfeeding or planning to breastfeed.

In some cases, alternative acne treatments with established safety profiles in pregnancy and breastfeeding may be recommended. Always seek medical advice before making changes to your therapy.

FAQ

How long does it take to see results from Aczone?

Many people notice improvements after several weeks of regular use, but responses vary. If you do not see any benefit after a reasonable period, or if your skin becomes more irritated, speak with your clinician to review the plan.

What should I do if I forget a dose?

Apply the gel as soon as you remember, unless it is nearly time for your next scheduled dose. Do not double the dose to make up for a missed one. If you are unsure, contact your pharmacist or clinician for guidance.

Can I use Aczone with other acne medications?

Aczone may be used with other acne treatments as advised by your clinician, but some combinations can increase irritation or reduce effectiveness. Always follow medical guidance about timing and layering of products.

What if my skin is very sensitive to Aczone?

If you have sensitive or reactive skin, discuss with your clinician. They may suggest using a smaller amount, applying less frequently, or trying a different treatment to reduce irritation.

Is Aczone suitable for teenagers?

Aczone can be prescribed to teenagers if acne is a concern, but suitability depends on individual skin type and medical history. A clinician will assess the best option for a young person and provide instructions accordingly.

What should I do if I experience skin irritation?

If irritation is mild, you may continue with careful monitoring as advised by your clinician. If irritation is persistent or severe, stop using the product and contact your clinician for advice.

Do I need a prescription to get Aczone in New Zealand?

Access to Aczone may require a prescription depending on local rules. Check with your pharmacist or clinician to confirm how it can be obtained in your area.

Should I avoid sun exposure while using Aczone?

Sun sensitivity can increase with treatment. Use sunscreen on treated areas, wear protective clothing, and limit direct sun exposure as advised by your clinician.

How should I store Aczone?

Store Aczone at room temperature, away from heat and moisture. Do not freeze the gel and keep it out of reach of children. Check the packaging for any specific storage instructions.

What should I do if I swallow the gel?

If the gel is swallowed, seek medical advice promptly. Do not induce vomiting unless instructed by a healthcare professional. Contact local health services for guidance on next steps.

Can I wear makeup over Aczone?

You may apply makeup after the gel has dried, but wait until it is fully absorbed and do not rub the skin aggressively. If you experience irritation, reduce or pause use and discuss with your clinician.

Sources

Official patient information leaflets for Aczone and dapsone gel provide guidance on use, safety, and administration. These leaflets are the primary source for patient-facing details about the medicine.

New Zealand Medicines and Medical Devices Safety Authority (Medsafe) information informs regulatory context and safety considerations for medicines available in New Zealand. It is a key reference for prescribing rules and patient safety notices.

DermNet NZ and related dermatology resources offer general information about acne management, skin care practices, and common considerations when using topical acne therapies. While not a substitute for medical advice, they help explain how these medicines fit into a broader skin care plan.

Pharmac consumer guidance and local pharmacy practice articles provide practical tips on storage, handling, and when to seek professional advice for topical acne treatments in a New Zealand setting.

✈️

Airmail

14–21 days. Free from NZD338.83 .

Express delivery

5–9 days. NZD50.82

🔒

Crypto discount

−10% when paying with cryptocurrency.

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Reorder discount

−10% on all repeat orders.

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All orders are packed in neutral, unbranded boxes with no product name on the outside.